Dr. Howard Smith Oncall

Vidcast:  https://www.instagram.com/p/C4gS3KPLeVF/ Using a clever DNA barcoding selection system, bioengineers and immunologists at the University of Pennsylvania have identified lipid nanoparticles or LNPs that selectively accumulate in the lungs.  These molecules than become ideal transport mechanisms for delivery of mRNA to lung tissues.  Such mRNA can be specifically created to trigger the production of therapeutic agents to treat lung diseases including cancer. These lipid nanoparticle mRNA transporters may be familiar to you as they have already been used in the creation of CoVid mRNA vaccines.  The CoVid vaccine lipid nanoparticles as a group are non-specific in their targeting.  These new LNPs may see far more broad deployment for not only vaccines but as carriers for other molecules to other organs as the scope of precision and guided therapy expands. https://www.nature.com/articles/s41467-024-45422-9 #lnp #lipids #nanomedicine #lung #mRNA #vaccines