Bulletproof Radio

This episode reveals how one simple breath pattern can rewire your nervous system, regulate stress in seconds, and become your most powerful tool for human performance and longevity. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Aaron Alexander, a world-renowned human performance coach, manual therapist, and creator of The Align Method. Aaron has worked with elite athletes, high-level entrepreneurs, and celebrity performers to transform the way they move, breathe, and live in their bodies. He merges structural alignment, functional medicine, emotional awareness, and deep nervous system science to help people get unstuck, physically and emotionally. Together, they explore the science and strategy behind breathwork, vagal tone, posture, and fascia, revealing how the body stores trauma, how breath shifts brain states, and how physical misalignment can sabotage mental clarity, energy, and even mitochondr

This episode reveals the ancient health protocols Western medicine forgot, and how they are now being used to heal stress, rewire the nervous system, and radically improve human performance. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Mona Sharma, a renowned Ayurvedic practitioner, celebrity wellness expert, and functional medicine advocate who grew up in a Canadian ashram. Mona combines ancient Vedic practices with cutting-edge science to help her clients, including Will Smith and other high-profile figures, achieve high performance, emotional resilience, and deep-rooted healing. She translates the 5,000-year-old system of Ayurveda into practical strategies anyone can use to optimize health in today’s chaotic world. Together, they explore how Ayurvedic biohacking techniques like breathwork, circadian alignment, detoxification, and herbal medicine are now being validated by data in neuroscience, mi

You’re being programmed, and it’s more subtle and pervasive than you think. From invisible influence to psychological manipulation, this episode shows you how to recognize when your thoughts aren’t really yours. Host Dave Asprey uncovers the hidden science of mind control with Harvard historian Rebecca Lemov. She is a professor of the History of Science at Harvard University and one of the world’s leading experts on psychological manipulation, surveillance science, government experimentation, and Cold War brainwashing programs. Her groundbreaking research into MK Ultra, behavioral psychology, and reeducation campaigns reveals exactly how external forces hijack your thoughts, emotions, and decisions, without you knowing. They break down how mind control evolved from CIA-funded brain implants and LSD experiments into today’s algorithmic persuasion, trauma-based manipulation, and tech-driven influence. This episode gives you practical tools to defend your thoughts, upgrade your awareness, and reclaim y

Your brain runs slow when it’s running on the wrong fuel. In this episode of The Human Upgrade, Dave Asprey sits down with Geoffrey Woo, Stanford-trained computer scientist and founder of Ketone-IQ, to reveal the high-performance brain fuel once reserved for Special Forces and elite athletes. Discover how ketones helped operators in combat zones sharpen focus, recover faster, and boost reaction speed by up to 30%. Learn why glucose falls short, how to hack your mitochondria for better cognition, and what it takes to unlock rapid-fire thinking on demand. This is brain energy for people who want to win, at life, work, and everything in between. Whether you’re fasting, flying, or facing real pressure, ketones flip the switch. You’ll Learn: • Why ketones beat glucose for focus, speed, and mental clarity • How Special Forces use ketones to recover brain function under stress • The truth about esters, salts, and the new wave of ketone diols • How ketones support faster t

Your cells are starving. Not for food—but for oxygen. In this episode of The Human Upgrade, Dave Asprey sits down with Dr. Jason Sonners, world-renowned hyperbaric expert and regenerative medicine pioneer, to reveal how controlled oxygen under pressure is becoming one of the most powerful tools in anti-aging and performance science. You’ll learn how hyperbaric oxygen therapy (HBOT) triggers stem cell activation, rewires your epigenome, boosts mitochondrial energy, and reverses biological aging—if you use it the right way. Jason shares breakthrough findings from his latest PhD research comparing low- and high-pressure chambers, with surprising results on inflammation, telomeres, cognitive performance, and recovery speed. This is next-gen longevity—measurable, stackable, and customizable. From sleep upgrades and HRV boosts to stacking HBOT with fasting, methylene blue, or red light, this episode dives into what it takes to oxygenate your biology at the deepest level. You’

Your brain has a gear you’ve never touched. Psychedelics can shift you into it. In this episode of The Human Upgrade, Dave Asprey uncovers how high-performance psychedelic mushrooms help you access flow states, rewire your brain, and enhance clarity, energy, and emotional resilience. This is next-level biohacking rooted in real science. You will learn how to use psychedelics with intention. When to microdose. When to go deep. How to stack them with nootropics for even stronger results. Dave breaks down the latest research on psilocybin, brain plasticity, trauma release, and how to turn ancient compounds into modern performance tools. What You Will Learn in This Episode: • How psychedelic shrooms unlock flow, focus, and creative power • Why psilocybin boosts neuroplasticity, mood, and emotional healing • Microdosing vs. full-dose: what works, when, and how • How to stack psychedelics with nootropics and other biohacks • The newest research on brain optimization and

Low testosterone is sabotaging your health, motivation, and longevity. Diet alone will not fix it. In this episode of The Human Upgrade, Dave Asprey sits down with Shalin Shah, CEO of Marius Pharmaceuticals, to expose the truth about testosterone decline in both men and women. They break down why testosterone is crashing worldwide, why natural fixes almost always fail, and how the latest science finally makes testosterone therapy safer, simpler, and more effective than ever before. You will discover why testosterone is essential for dopamine, brain function, sleep, muscle, libido, and mitochondrial health. Fixing your levels can reverse fatigue, brain fog, poor motivation, and slow aging itself. Shalin reveals how new oral testosterone technology (Kyzatrex®) overcomes the dangers of old therapies and restores natural hormone rhythms without needles, creams, or dangerous side effects. What You Will Learn in This Episode: • Why testosterone matters for men and women at every age&nb

Your environment is rewiring your hormones, fertility, and long-term health without your consent. In this episode of The Human Upgrade, Dave Asprey sits down with Dr. Aly Cohen, board-certified rheumatologist, integrative medicine specialist, and environmental health educator. Together they expose how common toxins in plastics, pesticides, drinking water, personal care products, and food packaging are hijacking your biology. Dr. Cohen explains how daily chemical exposures contribute to autoimmune disease, thyroid dysfunction, hormone imbalance, infertility, obesity, cancer, and accelerated aging. You will learn how to identify hidden endocrine disruptors, spot surprising sources of microplastics and PFAS (“forever chemicals”), and apply science-backed detox strategies to protect your hormones, fertility, metabolism, and longevity. What You’ll Learn in This Episode: • How chemicals in household, cleaning, and beauty products disrupt hormones • The link between environmental t

What if you could reverse the age of your heart...without leaving home? In this episode of The Human Upgrade, Dave Asprey sits down with Dr. Anurag Singh, Chief Medical Officer of Timeline, to reveal groundbreaking science that targets cardiovascular aging at the cellular level. You’ll discover how mitochondrial decline drives heart failure, why postmenopausal women face skyrocketing cardiac risks, and how one powerful molecule, Urolithin A, can rejuvenate your heart’s energy systems. Dr. Singh shares clinical research showing how Urolithin A improves mitochondrial function, boosts endurance, and may even reverse biological aging markers in the heart. You’ll also learn how simple lifestyle biohacks, combined with cellular nutrition, can protect your cardiovascular health and extend your healthspan. What You’ll Learn in This Episode: • The link between mitochondrial decline and heart failure • Why women’s cardiac risk skyrockets after menopause • How Urolithin A stimulates mi

What if a laser could help a child speak for the first time—or reverse an “incurable” brain condition? In this episode of The Human Upgrade, Dave Asprey talks with Dr. Brandon Crawford, a leading neurotherapist and founder of 528 Innovations, about the emerging science of laser therapy for the brain and body. You’ll learn how light—when precisely pulsed and targeted—can rewire brainwaves, heal trauma, and even influence states of consciousness. Dr. Crawford explains how specific laser frequencies are being used to modulate brain states, activate the vagus nerve, improve mood, restore gut-brain communication, and support recovery from conditions like autism and ALS. From EEG shifts to structured water and mitochondrial signaling, this conversation dives deep into biohacking’s most advanced light-based tech. What You’ll Learn in This Episode: • How laser therapy rewires brainwaves for mood, focus, and clarity • The exact brain regions linked to embodiment, intuition, and flow 

What if mitochondria weren’t just energy engines — but conscious beings guiding your survival and evolution? In this episode, Dave Asprey sits down with Zach Bush, MD, to uncover a radical new science of cellular intelligence. Together, they reveal how your mitochondria, microbiome, and genetic memory do far more than support survival—they actively shape consciousness, drive healing, and accelerate human evolution. You’ll discover why chronic disease, fatigue, brain fog, and emotional trauma often trace back to lost cellular communication—and how restoring that network can unlock radical resilience, deeper energy, and true longevity. Through the lens of soil health, vibrational biology, light frequencies, and ancient microbial wisdom, Zach Bush shows why the future of biohacking demands reconnection to the deeper intelligence already alive inside you. What You’ll Learn in This Episode: • How mitochondria act as conscious messengers—not just energy factories—and why that changes everyt

You’ve probably heard of HIIT—but have you heard of “REHIT?”  This isn’t just another workout trend...it’s a new science-backed way to train with maximum efficiency and zero wasted time. If you’re still jogging, you’re wasting hours for minimal results. In this episode of The Human Upgrade, Dave Asprey sits down with Ulrich Dempfle, German-trained engineer and co-founder of CAROL Bike, to dismantle outdated cardio advice and introduce the 5-minute protocol that’s obliterating fitness myths. Forget the treadmill grind. REHIT (Reduced Exertion High-Intensity Training) exercising delivers: • 12% VO₂ max increase• 6x the fitness gains of daily jogging • 62% drop in diabetes risk • 5x more BDNF for brain power —all with just 8 minutes of effort per week. But was it? Ulrich unpacks the hard data, crushes the Zone 2 obsession, and shows how a brand-new way of exercising is giving explosive results—no matter your age or fitness level. What You’ll Learn in This Episode:&nbs

Your bloodwork looks normal. Your doctor says you’re fine. But you still feel exhausted, inflamed, anxious—or worse. In this episode, Dave Asprey talks with Dr. Daniel Pompa, a leading voice in cellular detox and root-cause healing, to expose the hidden stressors hijacking your energy, hormones, and metabolism—even when your labs say you’re healthy. Dr. Pompa shares his personal health collapse and reveals how cellular dysfunction, neurotoxicity, and hormone resistance drive the chronic fatigue epidemic. If you’ve ever felt dismissed by “perfect” bloodwork, this conversation will rewire how you think about sickness—and show you how to reclaim real, lasting wellness. What You’ll Learn in This Episode: • Why your bloodwork can be “perfect” while your cells are on fire • The overlooked hormone resistances sabotaging your energy and metabolism • The 3-legged stool of chronic illness—and what actually drives disease • What “upstream detox” really means, a

Most people run from stress. The world’s highest performers run toward it. Sébastien Page manages over $500 billion in global assets. He’s the CIO of one of the world’s largest investment firms, and he wrote The Psychology of Leadership while living under relentless pressure. His secret? He doesn’t avoid stress—he uses it as a tool for performance, clarity, and control. But here’s the twist: this isn’t just about boardrooms or billion-dollar trades. Whether you’re running a company, chasing a deadline, or just trying to stop procrastinating on your goals—this conversation will flip what you think you know about pressure, performance, and productivity. You’ll learn why trying to “relax your way to success” doesn’t work—and how to harness discomfort to create better decisions, higher output, and more resilience in every part of life. What You’ll Learn in This Episode: • The psychology of stress and why zero stress leads to burnout • How procrastination

Your DNA, health data, and digital identity are encrypted, monetized, and weaponized against you. But what if there was a way to take it back… and hack the system? In this mind-expanding episode, Dave sits down with two elite hacker-founders—Michael Tiffany, CEO of Fulcra.ai, and Vishakh, founder of Monadic DNA—to explore a radical shift in the way we store, protect, and use our most personal data. Together, they break down the Web3 tech stack powering this revolution. Enter Nillion, a distributed, privacy-preserving compute network that allows you to share and analyze your encrypted data… without ever giving it away. From genomic privacy to AI sovereignty, this episode exposes the hidden architecture of control—and how to escape it. You’ll learn how cutting-edge blockchain and cryptography are rewriting the rules of ownership, consent, and even identity itself. What You’ll Learn in This Episode: • Why your DNA is already in government databases

If your brain feels foggy, your mood swings like a pendulum, or your cravings seem to control you—this episode will flip what you think you know about your body and your mind. Because what if your thoughts… aren’t really yours? In this mind-altering episode of The Human Upgrade, Dr. Steven Gundry reveals a startling new theory: your gut microbiome might be controlling your thoughts. From addiction and depression to obesity and inflammation, the microbes living in your gut—bacteria, fungi, viruses, even parasites—may be pulling the strings on your brain chemistry, mood, and behavior. Dave Asprey and Dr. Gundry dive deep into The Gut-Brain Paradox, exposing how the gut-brain axis operates more like a microbial command center than a digestive system. You’ll learn why probiotic pills rarely work, how the wrong microbes can drive compulsive behavior, and how toxic foods, glyphosate, and antibiotics have turned our guts into neurological war zones. Most shocking of all? Microbes may not jus

If your hair is thinning, shedding, or simply not what it used to be—and nothing seems to work—this episode is for you. Because what if the story you’ve been told about balding… is wrong? For decades, hair loss has felt like fate: genetic, inevitable, untouchable. But science is catching up to something deeper—something root-level. What if the real culprit behind age-related hair loss is cellular dysfunction? And what if we could change that? In this episode, Dave Asprey uncovers the cellular biology of hair thinning with longevity researcher Carolina Reis Oliveira. You’ll learn how senescent cells (aka zombie cells) hijack your scalp, disrupt follicle function, and silently accelerate hair loss—and how a breakthrough peptide might stop it cold. Carolina reveals brand-new clinical research on OS-01, a molecule shown to increase hair density by 40% in just 6 months. But this isn’t a product pitch—it’s a paradigm shift. Together, they explore the hidden drivers of ha

What if you could rewrite the code of your personality—on command? Not just cope with anxiety, overthinking, or social exhaustion… but delete the traits holding you back and install better ones? This episode challenges everything you’ve been told about identity. Dave dives deep into the science of personality change to reveal why your habits, moods, triggers, and even sense of self aren’t fixed—they’re fluid. And more importantly: they’re up for grabs. Joining him is award-winning journalist from The Atlantic, Olga Khazan, author of Me, But Better, who spent years hacking her own mind—transforming high neuroticism, social avoidance, and chronic self-criticism into calm, confidence, and connection. Her personal experiment in identity rewiring became a roadmap for anyone who wants to feel different… and live differently. You’ll uncover the hidden mechanisms behind neuroticism, reactivity, and emotional spirals—and how to override them with real-time upgrades. Wh

Your brain isn’t broken—it’s underpowered. Energy crashes, poor sleep, brain fog, and emotional reactivity don’t just happen. You’re running on low voltage, and your mind pays the price. In this episode, Dave sits down with Dr. Patrick Porter, founder of BrainTap, to reveal how to reprogram your brain using light, sound, and guided visualization—no substances, no side effects, no BS. Dr. Porter breaks down how to activate gamma brainwaves, repair trauma loops, access psychedelic-like states, and boost cognitive performance by 19% in just six weeks. You’ll learn why most brains burn out decades too soon—and how to charge yours back up. What You’ll Learn in This Episode: • How to flood your brain with energy and wake it up • The light and sound protocol that mimics psychedelics—safely • What gamma brainwaves unlock—and how to generate them on demand • Why your default mode network traps you in stress and distraction • The BrainTap protocol that im

You think you’re helping your kid. You clear the path. You smooth the bumps. You make sure they never feel too sad, too bored, too uncomfortable. It feels like love. But what if it’s making them weak? In this episode, Dave Asprey sits down with bestselling author, TED speaker, and resilience expert Jennifer Cohen to reveal how today’s parenting norms are quietly producing the most anxious, dependent, and emotionally fragile generation in history—Gen Z. Whether you’re raising kids, managing young employees, or trying to understand the next generation—you’ll walk away from this episode with a new lens on resilience, responsibility, and real-world readiness. What You’ll Learn in This Episode: • Why Gen Z struggles with anxiety, confidence, and failure • How smartphones, safe spaces, and overparenting weaken resilience • The science behind boredom, chores, and grit-building discomfort • Why participation trophies are doing real psychological harm • The b