Jama Author Interviews: Covering Research In Medicine, Science, & Clinical Practice. For Physicians, Researchers, & Clinician

The Covenant of Water, Stanford University professor Dr Abraham Verghese’s long-awaited follow-up to his 2009 novel Cutting for Stone, traces the lives of a family in southern India negotiating forces of history, fate, and a genetic condition that takes the life of a member in each generation by drowning. JAMA Arts and Medicine Section Editor Michael Berkwits, MD, MSCE, talks with Dr Verghese about the novel’s clinical insights, the craft of writing fiction, the role of the humanities in medicine, of artificial intelligence in literature, and more. Related Content: “The Art of the Craft,” From The Covenant of Water

Major medical schools are no longer contributing data to the US News & World Report (USNWR) including more than half the schools that are currently ranked in the top 10 medical schools by the survey. In this podcast, JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, speaks with author Holly J. Humphrey, MD, from the Josiah Macy Jr Foundation in New York, about the recently published Viewpoint "Medical School Rankings—Bad for the Health of the Profession and the Public." Related Content: Medical School Rankings—Bad for the Health of the Profession and the Public

Differences among countries in how health care is organized could have implications for health equity. JAMA Associate Editor Karen Joynt Maddox, MD, MPH, and Bruce E. Landon, MD, MBA, MSc, professor of health care policy, Harvard Medical School, discuss whether treatment patterns and outcomes for patients presenting with acute myocardial infarction differ for patients with higher vs lower incomes across 6 countries. Related Content: Differences in Treatment Patterns and Outcomes of Acute Myocardial Infarction for Low- and High-Income Patients in 6 Countries

JAMA Executive Editor Greg Curfman, MD, speaks with Robert D. Truog, MD, MA, director of the Harvard Center for Bioethics, who describes the 2 approaches to the determination of death (cardiovascular death and brain death) and discusses the possibility that the determination of brain death may soon undergo substantial change, with important implications for organ transplantation. Related Content: The Uncertain Future of the Determination of Brain Death

Mary Arakelyan, MPH, and JoAnna Leyenaar, MD, PhD, MPH, vice chair of Research in Pediatrics at Dartmouth, discuss increases in pediatric mental health hospitalizations and suicide-related diagnoses over the past decade. Hosted by JAMA Associate Editor Tracy Lieu, MD, MPH. Related Content: Pediatric Mental Health Hospitalizations at Acute Care Hospitals in the US, 2009-2019. Related Content: Pediatric Mental Health Hospitalizations at Acute Care Hospitals in the US, 2009-2019

In 2011, the US Food and Drug Administration (FDA) announced a mandate to limit acetaminophen (paracetamol) to 325 mg/tablet in combination acetaminophen and opioid medications, with manufacturer compliance required by early 2014. In this podcast, JAMA Deputy Editor Mary M. McDermott, MD, interviews Jayme E. Locke, MD, MPH, and Babak J. Orandi, MD, PhD, about their JAMA study describing results of the FDA announcement on subsequent rates of hospitalizations for acute liver failure due to toxicity from acetaminophen-containing opioid drugs. Related Content: Association of FDA Mandate Limiting Acetaminophen (Paracetamol) in Prescription Combination Opioid Products and Subsequent Hospitalizations and Acute Liver Failure Moving the Needle to Reduce Acetaminophen (Paracetamol) Hepatotoxicity Acetaminophen (Paracetamol) and Acute Liver Failure

In this JAMA author interview, Peter J. Pronovost, MD, PhD, Chief Quality & Clinical Transformation Officer, University Hospitals, Cleveland, and an internationally recognized expert in patient safety, discusses his recent article in JAMA on “Misdiagnosis in the Emergency Department.” A new report from AHRQ underscores the seriousness of this problem. Related Content: Misdiagnosis in the Emergency Department

Interview with James Stevermer, MD, MSPH, USPSTF member and coauthor of Serologic Screening for Genital Herpes Infection: US Preventive Services Task Force Reaffirmation Recommendation Statement. Hosted by JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS. Related Content: Serologic Screening for Genital Herpes Infection: US Preventive Services Task Force Reaffirmation Recommendation Statement Reducing HSV-2 Morbidity and Mortality Reaffirmed USPSTF Recommendation Against Serologic Screening for Genital Herpes: Empowering Clinicians and Reducing Potential Harm Serologic Screening for Genital Herpes: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force Screening for Genital Herpes (Patient Page)

Susanna Naggie, MD, vice dean for research at Duke University's School of Medicine, discusses the ACTIV-6 trial of fluvoxamine for outpatient treatment of COVID-19 and outlines the role of platform trials during the pandemic. Hosted by JAMA Deputy Editor and Editorial Director for Equity Preeti Malani, MD, MSJ. Related Content: Effect of Fluvoxamine vs Placebo on Time to Sustained Recovery in Outpatients With Mild to Moderate COVID-19

In the wake of new legal challenges to race-conscious admission policies, JAMA Interim Executive Editor Gregory Curfman, MD, discusses racial and ethnic diversity in undergraduate and medical school admission policies with Roy H. Hamilton, MD, MS, from the Perelman School of Medicine, University of Pennsylvania. Related Content: Defending Racial and Ethnic Diversity in Undergraduate and Medical School Admission Policies

JAMA Deputy Editor Preeti Malani, MD, MSJ, discusses potential next-generation COVID-19 vaccines with Peter Marks, MD, PhD, director of the Center for Biologics Evaluation and Research at the US Food and Drug Administration. Related Content: Urgent Need for Next-Generation COVID-19 Vaccines

In this JAMA author interview, we speak with Robert M. Califf, MD, Commissioner of the FDA, about a remarkable advance in the technology of hearing aids. Dr Califf has done important work to secure the entry of over-the-counter hearing aids into the market, providing a less expensive alternative to traditional hearing aids. In this interview, Dr Califf tells the story of how this technology has finally been made available to the public. Related Content: Over-the-counter Hearing Aids: From Research to Policy to Practice

Interview with Chris Zielinski, Visiting Research Fellow and Faculty of Health and Wellbeing at the University of Winchester, UK, James Kigera, Editor-in-Chief, Annals of African Surgery, and James Tumwine, Editor-in-Chief, African Health Sciences, authors of COP27 Climate Change Conference—Urgent Action Needed for Africa and the World. Hosted by JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD. Related Content: COP27 Climate Change Conference—Urgent Action Needed for Africa and the World Conflict and Climate Collide to Create an Acute Hunger Crisis for an Unprecedented 345 Million People Climate Justice and Health Children, Climate Justice, and Lessons From Puerto Rico

Interview with Gbenga Ogedegbe, MD, MPH, USPSTF member and coauthor of Screening for Obstructive Sleep Apnea in Adults: US Preventive Services Task Force Recommendation Statement. Hosted by JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS. Related Content: Screening for Obstructive Sleep Apnea in Adults Screening for Obstructive Sleep Apnea in Adults Screening for Obstructive Sleep Apnea in Adults Screening for Obstructive Sleep Apnea USPSTF Updates Recommendation for Obstructive Sleep Apnea Screening in Adults

Interview with Carol Mangione, MD, MSPH, USPSTF chair and coauthor of Hormone Therapy for the Primary Prevention of Chronic Conditions in Postmenopausal Persons: US Preventive Services Task Force Recommendation Statement. Hosted by JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS. Related Content: Hormone Therapy for the Primary Prevention of Chronic Conditions in Postmenopausal Persons Hormone Therapy for the Primary Prevention of Chronic Conditions in Postmenopausal Persons Menopausal Hormone Therapy for Prevention of Chronic Conditions

Interview with Martha Kubik, PhD, RN, USPSTF member and coauthor of Screening for Anxiety in Children and Adolescents: US Preventive Services Task Force Recommendation Statement, and Screening for Depression and Suicide Risk in Children and Adolescents: US Preventive Services Task Force Recommendation Statement. Hosted by JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS. Related Content: Screening for Anxiety in Children and Adolescents Screening for Anxiety in Children and Adolescents Screening for Depression and Suicide Risk in Children and Adolescents Screening for Depression and Suicide Risk in Children and Adolescents Screening for Anxiety in Children and Adolescents Screening for Pediatric Anxiety Disorders

In this JAMA Author Interview, JAMA Interim Executive Editor Greg Curfman, MD, speaks with Mary M. McDermott, MD, professor of medicine at Northwestern University Feinberg School of Medicine, on current therapies for peripheral artery disease and a new clinical trial she directed on the use of telmisartan, an angiotensin receptor blocker, for patients with peripheral artery disease. Related Content: Effect of Telmisartan on Walking Performance in Patients With Lower Extremity Peripheral Artery Disease

Interview with Katrina E. Donahue, MD, MPH, USPSTF member and coauthor of Screening for Syphilis Infection in Nonpregnant Adolescents and Adults: US Preventive Services Task Force Reaffirmation Recommendation Statement. Hosted by JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS. Related Content: The Critical Need to Modernize Syphilis Screening Screening for Syphilis Infection in Nonpregnant Adolescents and Adults Screening for Syphilis Infection in Nonpregnant Adults and Adolescents Screening for Syphilis

JAMA Network Open Editor Frederick Rivara, MD, MPH, discusses approaches to reducing firearm violence with several JAMA Viewpoint authors: Sandro Galea, MD, DrPH (Boston University), Elinore J. Kaufman, MD, MSHP (University of Pennsylvania), and Roger A. Mitchell Jr, MD (Howard University). Topics include the state-level response to firearm-related harms, the paucity of data on firearm violence, and the pervasive health effects of firearm violence on neighborhoods and in the carceral system. Related Content: The Epidemiology of Firearm Injuries in the US: The Need for Comprehensive, Real-time, Actionable Data Violence and the Carceral State: A Public Health Continuum State Firearm Laws and Firearm-Related Mortality and Morbidity Examining the Impact of Firearm Safety Laws on Suicides Physicians and EMS Who Responded to Mass Shootings Develop Consensus Recommendations for Improving Care Approaches to Reducing Firearm Violence

CRISPR genome editing is a revolutionary technology that can be used to make highly targeted changes in DNA in living cells. JAMA Associate Editor W. Gregory Feero, MD, PhD, Maine Dartmouth Family Medicine Residency, and Matthew J. Kan, MD, PhD, University of California San Francisco, discuss how CRISPR works and how CRISPR-based technologies are being used in ongoing trials to treat a wide variety of medical conditions. Related Content: Treatment of Genetic Diseases With CRISPR Genome Editing With First CRISPR Trials, Gene Editing Moves Toward the Clinic