Jama Author Interviews: Covering Research In Medicine, Science, & Clinical Practice. For Physicians, Researchers, & Clinician

  • Autor: Vários
  • Narrador: Vários
  • Editor: Podcast
  • Duración: 219:43:42
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Sinopsis

Engaging and topical conversations with authors of research, clinical reviews, and opinion pieces published in JAMA. Subscribe for the latest information, ideas, and innovations in clinical medicine and health policy.

Episodios

  • Life Support and Outcomes in Patients Admitted to Intensive Care Units

    14/04/2025 Duración: 19min

    Nationwide data are unavailable regarding changes in intensive care unit (ICU) outcomes over the past 10 years, limiting understanding of practice changes. Authors Emily Moin, MD, MBE, and Scott D. Halpern, MD, PhD, MBE, of the University of Pennsylvania join JAMA Associate Editor Christopher W. Seymour, MD, MSc, to discuss how ICU care and outcomes have changed in the US over the past decade. Related Content: Use of Life Support and Outcomes Among Patients Admitted to Intensive Care Units

  • Increases in Invasive Group A Streptococcal Infections

    07/04/2025 Duración: 13min

    The incidence of invasive group A streptococcal infections has risen in the US. Similar observations have been reported in other parts of the world. Authors Joshua Osowicki, MBBS, PhD, of Murdoch Children’s Research Institute and Theresa L. Lamagni, MSc, PhD, of the United Kingdom Health Security Agency join JAMA Deputy Editor Preeti Malani, MD, MSJ, to discuss the public health challenge posed by group A strep. Related Content: Invasive Group A Streptococcal Disease in the US Invasive Group A Streptococcal Infections in 10 US States

  • Preventive Health Care Among Adults Eligible for Lung Cancer Screening

    02/04/2025 Duración: 09min

    Less than 20% of patients eligible for lung cancer screening get screened in the US. A recent study examined whether adults eligible for lung cancer screening engage in screening for other types of cancer. Coauthor Chi-Fu Jeffrey Yang, MD, of Harvard Medical School joins JAMA Deputy Editor Tracy Lieu, MD, to discuss. Related Content: Preventive Health Care Use Among Adults Eligible for Lung Cancer Screening in the US

  • Cardiac Arrests During Long-Distance Running: What’s Changed?

    30/03/2025 Duración: 15min

    Despite increased participation in US long-distance running races, cardiac arrest incidence remains stable. Authors Jonathan Kim, MD, MSc, of Emory University, and Aaron Baggish, MD, of the University of Lausanne Switzerland, discuss the RACER 2 study and compare results with initial findings published in the RACER 1 study from 13 years ago, with JAMA Associate Editor Gregory Marcus, MD, MAS. Related Content: Cardiac Arrest During Long-Distance Running Races

  • Inhaled Sedation With Sevoflurane for Acute Respiratory Distress Syndrome (ARDS)

    18/03/2025 Duración: 18min

    ARDS, which is characterized by hypoxemic respiratory failure and inflammatory injury to the lungs, has a mortality rate of 30% to 40%. Balasubramanian Venkatesh, MD, of the George Institute for Global Health joins JAMA Deputy Editor Kristin Walter, MD, MS, to discuss the effects of inhaled sedation with sevoflurane for patients with moderate to severe ARDS. Related Content: Sevoflurane Sedation in Acute Respiratory Distress Syndrome Inhaled Sedation in Acute Respiratory Distress Syndrome

  • New FDA Pulse Oximetry Guidance: Strengths and Weaknesses

    05/03/2025 Duración: 16min

    The US Food and Drug Administration (FDA) issued new draft regulatory guidance for pulse oximeters related to skin pigment. The guidance is a step forward but it may have unintended consequences. Authors Michael Lipnick, MD, and Philip Bicker, MD, PhD, professors of anesthesia at University of California, San Francisco, discuss this and more with JAMA Executive Editor Gregory Curfman, MD. Related Content: Pulse Oximetry and Skin Pigmentation—New Guidance From the FDA Adherence to FDA Guidance on Pulse Oximetry Testing Among Diverse Individuals, 1996-2024 Addressing Racial and Ethnic Bias in Pulse Oximeters—A Wicked Problem Evaluating the Accuracy of Pulse Oximetry in Children According to Race

  • Combining CAC Score With Treatment on Plaque Progression in Familial Coronary Artery Disease

    05/03/2025 Duración: 10min

    The CAUGHT-CAD randomized clinical trial sought to determine whether a CAC score-informed strategy could slow the progression of coronary plaque volume. Author Thomas H. Marwick of the Baker Heart & Diabetes Institute joins JAMA Associate Editor Pradeep Natarajan to discuss "Effects of Combining Coronary Calcium Score With Treatment on Plaque Progression in Familial Coronary Artery Disease." Related Content: Effects of Combining Coronary Calcium Score With Treatment on Plaque Progression in Familial Coronary Artery Disease Cardiac CT Calcium Score Coronary Artery Calcium Testing—Too Early, Too Late, Too Often Filling the Evidence Gaps Toward a Coronary Artery Calcium-Guided Primary Prevention Strategy

  • Evaluating Treatments for Amyotrophic Lateral Sclerosis

    17/02/2025 Duración: 22min

    The HEALEY ALS platform is an innovative first attempt at platform trials in ALS, looking to slow ALS disease progression. Author Sabrina Paganoni, MD, PhD, of Massachusetts General Hospital and Harvard Medical School, discusses results of the first 4 drug regimens from this platform trial and how this study design makes efficient use of resources, with JAMA Deputy Editor Christopher Muth, MD. Related Content: Platform Clinical Trials for the Efficient Evaluation of Multiple Treatments Pridopidine in Amyotrophic Lateral Sclerosis Platform Trials in ALS Verdiperstat in Amyotrophic Lateral Sclerosis Efficacy and Safety of Zilucoplan in Amyotrophic Lateral Sclerosis CNM-Au8 in Amyotrophic Lateral Sclerosis

  • US Health Care Spending by Health Condition and County—What Drives Variation?

    14/02/2025 Duración: 13min

    Understanding health conditions with the most spending and variation across locations and over time is important for identifying trends, inequalities, and strategies for lowering health spending. Joseph Dieleman, PhD, of the University of Washington speaks with JAMA Associate Editor Karen Joynt Maddox, MD, MPH, about county-level variation in health care spending across the US. Related Content: Tracking US Health Care Spending by Health Condition and County

  • Supporting Children and Families in an Era With Abortion Restrictions

    13/02/2025 Duración: 11min

    Two recent studies published in JAMA provide evidence about the effects of state-level abortion restrictions on birth rates and infant mortality. Author Alyssa Bilinski, PhD, MSc, of Brown University School of Public Health joins JAMA Deputy Editor Tracy Lieu, MD, to discuss her related Editorial "Abortion May Be Controversial—Supporting Children and Families Need Not Be." Related Content: Abortion May Be Controversial—Supporting Children and Families Need Not Be

  • Evaluating Comprehensive Models–Challenges and Innovations in Dementia Care

    29/01/2025 Duración: 17min

    Contemporary models of dementia care are multidisciplinary and aim to bridge medical and social services. Julie P. W. Bynum, MD, MPH, of the University of Michigan speaks with JAMA Deputy Editor Christopher C. Muth, MD, about 2 trials—the D-CARE and IN-PEACE trials—that evaluated care models to support people diagnosed with dementia and their caregivers. Related Content: Challenges and Innovations in Dementia Care—Evaluating Comprehensive Models Health System, Community-Based, or Usual Dementia Care for Persons With Dementia and Caregivers Palliative Care Program for Community-Dwelling Individuals With Dementia and Caregivers

  • Intra-Arterial Thrombolytics Following Thrombectomy for Ischemic Stroke

    13/01/2025 Duración: 11min

    Two new trials published in JAMA evaluate the efficacy of periprocedural intra-arterial thrombolytics after successful endovascular thrombectomy for patients with acute ischemic stroke. Diederik Dippel, MD, PhD, of Erasmus University Medical Center discusses this and more with JAMA Deputy Editor Christopher C. Muth, MD. Related Content: Intra-Arterial Thrombolytics During Thrombectomy for Ischemic Stroke—End of the Story or a New Beginning? Intra-Arterial Tenecteplase Following Endovascular Reperfusion for Large Vessel Occlusion Acute Ischemic Stroke Intra-Arterial Urokinase After Endovascular Reperfusion for Acute Ischemic Stroke

  • Impact of Private Equity Acquisition on Patient Care Experience in US Hospitals

    09/01/2025 Duración: 13min

    Private equity acquisitions of health care facilities have rapidly increased over the past decade. However, little is known about the effects of these acquisitions on patient experience. Author Rishi K. Wadhera, MD, MPP, MPhil, of Harvard Medical School discusses this topic with JAMA Associate Editor Karen Joynt Maddox, MD, MPH. Related Content: Changes in Patient Care Experience After Private Equity Acquisition of US Hospitals

  • Asthma Endotypes Based on Nasal Epithelial Biopsies in School-Aged Youth

    02/01/2025 Duración: 11min

    Certain CD4+ T-cell subtypes play a role in asthma. Characterizing asthma endotypes in diverse groups is important to help develop effective therapies for youth with asthma. Author Juan C. Celedon, MD, DrPH, University of Pittsburgh, Department of Pediatrics, discusses this and more with JAMA Deputy Editor Kristin L. Walter, MD, MS. Related Content: Transcriptomic Profiles in Nasal Epithelium and Asthma Endotypes in Youth

  • Dental Benefits and Medicare Advantage Plans

    26/12/2024 Duración: 11min

    Most Medicare Advantage (MA) plans offer dental care coverage as a supplemental benefit. However,few beneficiaries are enrolled in an MA plan that provides comprehensive dental benefits. Lisa Simon, MD, DMD, discusses this and more with JAMA Deputy Editor Kristin L. Walter, MD, MS. Related Content: Availability of Dental Benefits Within Medicare Advantage Plans by Enrollment and County

  • 2024 Update on Long COVID Classification and Symptom List

    18/12/2024 Duración: 12min

    Long COVID is now defined as a heterogeneous, infection-associated chronic condition present for at least 3 months after SARS-CoV-2 infection. Author Leora Horwitz, MD, MHS, of NYU Grossman School of Medicine joins JAMA Executive Editor Gregory Curfman, MD, to discuss the JAMA article "2024 Update of the RECOVER-Adult Long COVID Research Index." Related Content: 2024 Update of the RECOVER-Adult Long COVID Research Index Characterizing Long COVID in Children and Adolescents

  • Camrelizumab vs Placebo With Chemotherapy as Neoadjuvant Treatment in Triple-Negative Breast Cancer

    13/12/2024 Duración: 15min

    Triple-negative breast cancer accounts for around 15% of breast cancers. Zhi-Ming Shao, MD, of Fudon University, joins JAMA Oncology Editor in Chief and JAMA Deputy Editor Nora Disis, MD, to discuss "Camrelizumab vs Placebo in Combination With Chemotherapy as Neoadjuvant Treatment in Patients with Early or Locally Advanced Triple-Negative Breast Cancer: The CamRelief Randomized Clinical Trial." Related Content: Camrelizumab vs Placebo in Combination With Chemotherapy as Neoadjuvant Treatment in Patients With Early or Locally Advanced Triple-Negative Breast Cancer

  • HIV Treatment and Prevention: Updated Recommendations

    01/12/2024 Duración: 15min

    New antiretroviral drugs and formulations continue to become available for the prevention and management of HIV infection. Author Rajesh T. Gandhi, MD, joins JAMA Deputy Editor Preeti Malani, MD, MSJ, to discuss these new approaches for HIV. Related Content: Antiretroviral Drugs for Treatment and Prevention of HIV in Adults: 2024 Recommendations of the International Antiviral Society–USA Panel Advances in Treatment and Prevention of HIV

  • The Impacts of Severe Maternal Morbidity

    25/11/2024 Duración: 13min

    A new JAMA study examines the association between severe maternal morbidity in a first birth and the probability of a subsequent birth. Authors Neda Razaz, PhD, and Eleni Tsamantioti, MD, MMedSc, both from the Karolinska Institute in Sweden, discuss this and more with JAMA Associate Editor Melissa A. Simon, MD, MPH. Related Content: Association of Severe Maternal Morbidity With Subsequent Birth Severe Maternal Morbidity and Subsequent Birth—Understanding and Informing a Woman’s Choice

  • Zerlasiran, a Small-Interfering RNA That Targets Lipoprotein(a)

    18/11/2024 Duración: 14min

    Elevated lipoprotein(a) levels increase the risk of atherosclerotic cardiovascular disease (ASCVD) and aortic stenosis. Cleveland Clinic’s Steven E. Nissen, MD, speaks with JAMA Executive Editor Gregory Curfman, MD, about how zerlasiran produced more than 80% reductions in time-averaged lipoprotein(a) concentration. Related Content: Zerlasiran—A Small-Interfering RNA Targeting Lipoprotein(a)

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